I've looked into this for the PS3. The console supports the use of standard mice and keyboards via the USB ports, however they only really work for menu navigation and text input in the system menu screens. They don't work in games unless the game is specifically designed to support them. Few are.
If you're really keen on using a mouse, you can (or could... May be discontinued now) buy a very weird and expensive controller whose name escapes me right now, but is basically a standard pad cut in half with the right stick converted into a mouse rollerball and the left looking like the Wiimote nunchuck. I'll Google it for you once I'm off the shitter.
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