Hannibal Lecter: "You know what you look like to me, with your good bag and your cheap shoes? You look like a rube. A well scrubbed, hustling rube with a little taste. Good nutrition has given you some length of bone, but you're not more than one generation from poor white trash, are you, Agent Starling? And that accent you've tried so desperately to shed? Pure West Virginia. What's your father, dear? Is he a coal miner? Does he stink of the lamp? You know how quickly the boys found you... all those tedious sticky fumblings in the back seats of cars... while you could only dream of getting out... getting anywhere... getting all the way to the FBI."
(Not strictly a one liner, more of a multi liner. I once memorised the whole paragraph and used it as a chat up line in 'Flicks' one night to some doris (changed the names and country references to a certain Hampshire area). She looked at me as though I had just eaten her parents then murdered her grandparents with a shovel. Still got me legs blown up though as she said it was the most original chat up line she had ever heard and was intrigued weather I would remove her skin and parade around in it like a 'posh trench coat').
Hannibal Lecter: "I ate his liver with some fava beans and a nice chianti".
"Inspector Harry Callahan," (Clint Eastwood) cynical, world-weary, wisecracking, irreverent, chick magnet San Francisco police detective who carries a Smith & Wesson M29 .44 magnum revolver (a somewhat dubious choice for a police weapon) in "Dirty Harry."
Callahan chases down an armed baddie, corners the baddie at close quarters, points the cannon at him. Baddie tries to decide whether to go for his own gat.
Callahan lays out the odds for the baddie (approximately and from memory)
"You're probably asking yourself, 'did he fire five shots at me or six?' Well, to tell you the truth, in all the excitement, I lost track of that myself.
"But seeing as how this is a .44 magnum, the most powerful handgun in the world, and could blow your head clean off your shoulders, you should be asking yourself 'do I feel lucky?'